Is it possible to block iframe ads in the player?

Question

contextual advertising

There was a question of such a plan:
For example, we have a player that parses video through an iframe, it has a 15-second advertisement before watching a movie, a player from wolves:

advertising before watching such a plan:


So, is it possible to block such ads through any scripts at all? directly installed on the site itself.

For example, AdBlock - removes ads (the black window only remains without ads) and there is a 15 second timer. At the same time, ADGUARD completely removes ads from the player and viewing starts immediately after pressing the play button.

Chet thought, if the same adblock somehow hides the ad frame, then maybe this can be done somehow with a script? Or is it unrealistic?