Why is nginx throwing a 404 error?

Question

Nginx

Good afternoon. I use ISP Lite, I did not find nginx settings in it.
So here's the question: I have
almost 2000 hosts on my site (downloads, constant database queries), and vooo, how can I increase the load capacity?
The site throws out:

404 Not Found
nginx/1.8.0

Can that it is necessary to configure in virtual hosts?

Answer 1

Logs to the studio where 404 is.