How to select several audiences for targeting in FB at once?

Question

Facebook

Friends, tell me, please, is it possible to specify targeting settings when creating a campaign in FB: for subscribers and their friends? and not separately or one or the other?
If I use expanded combinations, then on the contrary, they narrow the coverage https://monosnap.com/file/LJPKt2uXza...9Ish7wEpZkwCEW
, then the following happens:
- when I select only friends of people who are connected - coverage is 2,500,000
- when I additionally select just subscribers from above coverage narrows to 17,000
the question is how to choose the right followers and their friends?
Thank you!