How to prepare query in PHP PDO with IN condition?

Question

PHP

Hello.
Tell me, please, who knows.
On the backend, I connect to the sqlite database via PDO and form a query like:

select field1, field2, ...
from table1
where field1 in ('val1_1', 'val1_2', ... 'val1_N') 
and field2 in ('val2_1', 'val2_2', ... 'val2_N')

For which fields the request will be made and the number of searched values ​​is not known in advance.
How to use unnamed (?) pseudo-variables here, or do you just need to run each value through checking and escaping (like quote)?
What are good practices for preparing (prepare, execute) such queries?
Thank you.