Why is mysql connection closed in django?

Question

MySQL

I have a Telegram bot in Python using Django, the bot is constantly running and after a few hours the connection to the mysql database drops. Knocks out -

(2002, "Can't connect to local MySQL server through socket '/var/run/mysqld/mysqld.sock' (2)")

As far as I understand, this is due to the fact that the connection to the database is opened and can be open for a long time, am I right? If so, how can I properly close the connection, or what is the best thing to do in this case?
I've tried closing the connection via connection.close() from the django.db library after each bot command, but that doesn't help.
PS The service with the database crashes completely and does not want to be restarted, only a reboot on the server helps