What is the difference between NGINX configs in the context of using NGINX-Django?

Question

Django

What is the difference between NGINX configs in the context of using NGINX-Django?

server {
    location / {
        proxy_pass http://127.0.0.1:8000/;
    }
}

and

server {
    location / {
    include    uwsgi_params;
    uwsgi_pass localhost:8000;
    }
}