What is more appropriate to use for meaningful "conversations" with the bot?

Question

Python

I use the pyTelegrambotApi library, what should I use for meaningful responses from the bot, global variables or writing to the database and then reading?
An example of a conversation with a bot:
person:/start
bot:Hi, what's your name?
h: No
way b: Hello, No way!
db - sqlite3
python - 3.6
bot works on pythonAnywhere

Answer 1

https://groosha.gitbooks.io/telegram-bot-lessons/c...

Answer 2

https://habrahabr.ru/post/346606/