What are the Grid System guides for website layouts in 2017?

Question

Layouts and prototypes

What size standards does PX use for professional website layout design in 2017?
I really want to create the correct grid for drawing layouts in illustrator, but I can’t finally decide on the grid.
One thing is clear that 1024 is somehow small today, many screens are much larger ... and 1280 cannot be properly divided into 12 columns if you subtract the size of the scroll bar to eliminate the appearance of horizontal scrolling.
Professional designers and web developers, let me know about today's standards to finally close this topic)
Pixel Perfect layout is very important for me, because even the layout will look clearer if you use only integer multiples of 2m in PX values.
And the new illustrator 2017 allows you to just link to PX when transforming objects.
Only the grid is not enough normal))
There are several options.

Answer 1

According to the width of the layout, I would consult directly with the layout designer with whom I work. But the layout in the chandelier... why? The same Photoshop works with shapes (but if it doesn’t fit to integers and pixels even with a plugin, then I recommend grid for example 8px. And work according to the system of the selected grid and then there will be the maximum possible perfect).