W10 slows down, why?

Question

Windows

And so, good day to all. I've been sitting here for 6 hours in a row and I can't solve one problem... After cleaning the PC, the W10 began to hang very strongly in the flesh of a complete frieze.
I'll start from the beginning, today I decided to clean the PC, I'm not doing this for the first time and I know perfectly well what is attached to what and where. I disassembled, pulled out the SSD AND HDD, so I replaced the thermal paste, reset the BIOS (pulling out the battery), pulled out the RAM, etc. Then I returned everything to its place and launched it, it did not work. I danced with tambourines, changed the memory sticks in places and everything worked, I was delighted. After starting the PC, I decided to start Adobe Illustrator, while listening to music while the program was running, some kind of crackling happened with the music + the wireless mouse began to twitch across the screen. Warnings hit right away, since such effects never bode well, after literally 5 minutes of sitting for AI, everything was repeated in the flesh until the PC completely freezes. I rebooted it, started everything and decided to recreate the load and see the processes, after which I saw that the SSD disk was 100% loaded, it happened before, it was so that both the CPU AND RAM AND DISK were loaded at 100%, but there never was such a thing that there were friezes or glitches with sound / mouse. I started checking with ssd utilities, I didn’t find anything bad everywhere, the condition is good, before that I sat on Windows 7 for 3 years, it never happened. I didn’t find an answer in Google, maybe there’s a problem in the BIOS or somewhere else, I’ve already run out of ideas and I’m very worried about whether I could damage the system by cleaning the dust, although I’ve owned the PC for more than 4 years and spend it stable every 3 months same procedure, never happened before... I started checking with ssd utilities, I didn’t find anything bad everywhere, the condition is good, before that I sat on Windows 7 for 3 years, it never happened. I didn’t find an answer in Google, maybe there’s a problem in the BIOS or somewhere else, I’ve already run out of ideas and I’m very worried about whether I could damage the system by cleaning the dust, although I’ve owned the PC for more than 4 years and spend it stable every 3 months same procedure, never happened before... I started checking with ssd utilities, I didn’t find anything bad everywhere, the condition is good, before that I sat on Windows 7 for 3 years, it never happened. I didn’t find an answer in Google, maybe there’s a problem in the BIOS or somewhere else, I’ve already run out of ideas and I’m very worried about whether I could damage the system by cleaning the dust, although I’ve owned the PC for more than 4 years and spend it stable every 3 months same procedure, never happened before...
I5 3330 3.0ghzX4
8 DDR3
GTX650 1GB
SSD 128 SANDISK
HDD 1TB

Answer 1

Try disabling the indexing service (from which the disk is 100% loaded). Absolutely hellish contraption, it is impossible to work with it even on a good configuration.

Answer 2

Why was the CMOS reset? Are the settings the same as they were?

Answer 3

could I damage the system by cleaning the dust, although I have owned a PC for more than 4 years and every 3 months I consistently carry out the same procedure, this has never happened ...

Of course.
Does TRIM work on SSD? Is there a reserve? How full is the disk? And most importantly, what exactly is the disk loaded with? What program?