On the grid or not on the grid?

Question

Bootstrap

I call you, O Gods and Guru of layout.
The problem is that layout designers say “this layout is not built on a grid and they can’t layout like that on Bootstrap, since the block does not completely cover all the columns of the grid and there is an empty space on the right” (In blue - blocks, in red - grid, design - Responsive, bootstrap Block size = 4 columns - 20px. ).
In this regard, there are questions:
1. Is the layout built on a grid or not?
2. Is such an implementation possible as in the attached image?
3. If so, how much more difficult does it make the task?
Thanks

Answer 1

in general, this is nonsense, but the designer should have been more careful.
complicates for 10 minutes