Is it possible to do an enterprise on Node.js?

Question

Node.js

I read a little, to broaden my horizons, about server-side development on Node.js. The question arose - how suitable is it for developing a serious server-side API for which I usually use ASP.NET WebApi / C # / EntityFramework, multi-layer architecture, etc.?
Is there an example of a large and powerful API in Node.js?

Answer 1

see also koa 2 framework, much less writing using async/await