How to make random variables not repeated?

Question

Python

def spam():
    messages_test = int(messages)
    time_test = int(time)
    for i in range(messages_test):
        result1 = random.choice(messages_list1)
        result2 = result1
        result3 = result2
        result4 = result3
        result5 = result4
        result6 = result5
        pwa.keyboard.send_keys (tag, with_spaces=True)
        sleep(time_test/4)
        pwa.keyboard.send_keys (result1, with_spaces=True)
        sleep(time_test/4)
        pwa.keyboard.send_keys ("{ENTER}")
        sleep(time_test/2)

I use the PYWINAUTO library so that it prints the text, and RANDOM so that it selects random text from the list, but these words are often repeated (there are 100+ values ​​in the list).
How to make sure that they do not repeat?
I want result2 to be equal to the previous value of result1, result3 to be equal to the previous result2 (and so on).

Answer 1

Why is this at all?
numbers = random.sample(a, k=6)