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for PHP front-end
if WEB page development (JS framework) then prototype or JQuery
What do you understand by this concept? If RIA, then for example ExtJS. If something more lightweight - jQuery.
You are a little confused - PHP, RoR, and other languages are Back-End.
The frontend is JavaScript, Backbone.js, CoffeScript and others + Node.js appeared not so long ago, on which you can hang the entire Back-end UI and leave only the logic for the Back-end itself.
I would recommend learning Node.js, its future looks bright!
And if on the Back-end, then I would advise learning RoR or Python.
As @GearHead
rightly noted in the comment , the choice of the server language depends on the task at hand.
If you need real-time work and a strong coupling of the interface with the server (Open a window with new data to the user when they change on the server, using the direction from the server to the user), then Node.js (optimal), etc. - RoR, Python, .Net (Except for PHP, you can do it on it, but it will be an unnatural act of masochism, which sooner or later will lead to "neurosis" and "psychosis" of the server).
If a high workload of the project is expected and not "storing" but computational functionality (meaning not 2 * 2, but something more), it is better to choose from RoR, Python, .Net.
Successful use cases for Node.raindrop.io and tactoom.com
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