Why are emails not sent from the SMTP server (Axigen)?

Question

Mail server

I set up the Axigen mail server, I'm trying to send letters.
For some reason, the server is trying to send emails through port 25. Yandex correctly receives letters, but other mail services return an error. For example, sending a letter to mail.ru:

Relay mail 377B4B: connecting to 94.100.180.31:25
2018-11-07 09:07:48 +0300: Relay mail 377B4B: connected to 94.100.180.31:25
2018-11-07 09:07:48 +0300: << 220 mxs.mail.ru ESMTP ready 
2018-11-07 09:07:48 +0300: >> EHLO localhost.localdomain
2018-11-07 09:07:48 +0300: << 250-mxs.mail.ru
2018-11-07 09:07:48 +0300: << 250-SIZE 73400320
2018-11-07 09:07:48 +0300: << 250-8BITMIME
2018-11-07 09:07:48 +0300: << 250 STARTTLS
2018-11-07 09:07:48 +0300: >> STARTTLS
2018-11-07 09:07:48 +0300: << 220 2.0.0 Start TLS
2018-11-07 09:07:48 +0300: >> SSL: client hello, remote 94.100.180.31:25, version TLS 1.2 (0303)
2018-11-07 09:07:48 +0300: >> SSL: client hello, remote 94.100.180.31:25, 85 cipher suites: c030c02cc028c024c014c00a00a500a300a1009f006b006a0069006800390038003700360088008700860085c032c02ec02ac026c00fc005009d003d00350084c02fc02bc027c023c013c00900a400a200a0009e00670040003f003e0033003200310030009a0099009800970045004400430042c031c02dc029c025c00ec004009c003c002f00960041c011c007c00cc00200050004c012c008001600130010000dc00dc003000a00ff
2018-11-07 09:07:48 +0300: << SSL: server hello, remote 94.100.180.31:25, version TLS 1.2 (0303)
2018-11-07 09:07:48 +0300: << SSL: server hello, remote 94.100.180.31:25, cipher suite c030
2018-11-07 09:07:48 +0300: << SSL: server write cert, remote 94.100.180.31:25, version TLS 1.2 (0303)
2018-11-07 09:07:48 +0300: << SSL: server write cert, remote 94.100.180.31:25, certificate 1: serial 0F45C3E7A2B173B7E56B58A6EFAAA03C
2018-11-07 09:07:48 +0300: << SSL: server write cert, remote 94.100.180.31:25, certificate 2: serial 0546FE1823F7E1941DA39FCE14C46173
2018-11-07 09:07:48 +0300: >> EHLO localhost.localdomain
2018-11-07 09:07:48 +0300: << 250-mxs.mail.ru
2018-11-07 09:07:48 +0300: << 250-SIZE 73400320
2018-11-07 09:07:48 +0300: << 250 8BITMIME
2018-11-07 09:07:48 +0300: Start sending mail 377B4B
2018-11-07 09:07:48 +0300: >> MAIL FROM:<[email protected]>
2018-11-07 09:07:48 +0300: << 250 2.0.0 OK
2018-11-07 09:07:48 +0300: >> RCPT TO:<[email protected]>
2018-11-07 09:07:48 +0300: << 250 Go ahead
2018-11-07 09:07:48 +0300: >> DATA
2018-11-07 09:07:48 +0300: << 354 Go ahead. End your data with <CR><LF>.<CR><LF>
2018-11-07 09:07:48 +0300: >> .
2018-11-07 09:07:48 +0300: >> 2756 bytes and final dot written
2018-11-07 09:07:48 +0300: Release mail 377B4B
2018-11-07 09:07:49 +0300: << 550 non-local sender verification failed
2018-11-07 09:07:49 +0300: Error sending data for mail 377B4B; server response code: 550 (non-local sender verification failed)
2018-11-07 09:07:49 +0300: Set recipient <[email protected]> state to RELAY ERROR
2018-11-07 09:07:49 +0300: Delivery attempt completed for mail 377B4B; schedule for cleanup
2018-11-07 09:07:49 +0300: Set mail state to SENT
2018-11-07 09:07:49 +0300: >> QUIT
2018-11-07 09:07:49 +0300: Disconnected from 94.100.180.31

Answer 1

For some reason, the server is trying to send emails through port 25.

Because mail servers communicate with each other over 25/tcp

<< 550 non-local sender verification failed
2018-11-07 09:07:49 +0300: Error sending data for mail 377B4B; server response code: 550 (non-local sender verification failed)
2018-11-07 09:07:49 +0300: Set recipient state to RELAY ERROR

Does this mean anything to you?