What is the difference between win32 and win64 programming?

Question

Programming

They recommended a book on assembler. It deals with programming under 16-32 bit architectures (dos and win).
Now 64-bit systems are relevant.
Is it worth learning low-level programming from that book? Or look for something newer?
And what can you advise?
PS. The book is called "Assembly Language for Intel Processors".
P.S.S. I am not going to seriously engage in low-level programming. I want to study for general development, to understand how everything works at a lower level

Answer 1

Basically nothing. So feel free to study according to the book that was advised, and then study the features of x64 using other material.

Answer 2

Learning assembler and delving into the intricacies of programming under x16, x32 and x64, DOS and Windows is not a general development. This is serious work.
If you have this question and have free time - study. But without a real task and a serious project, you are unlikely to learn anything serious on your own.