What database to use for offline-first app?

Question

JavaScript

Node.js @6 server
I'm about to write a small multi-user crm. Offline-first is necessary not because it is fashionable, but because it is a great opportunity to work in a slow-intermittent Internet. (namely, these conditions will be)
React is chosen for the view, since it already has many ready-made components (which will be very useful) + isomorphism out of the box (which is not unimportant for the page load time)
As for the db, there are such options:
- Use PouchDB on client and server as replication is out of the box. But I don’t like nosql because I’m not doing a blog with 3 sections, but still any crm and I’m already used to sql queries that are convenient for compiling all kinds of reports and so on.
-Use PouchDB on client and MysqlDOWNhttps://github.com/kesla/mysqldown for mysql on the server, which can provide fast nosql on the client and convenient mysql on the server
I don't know any more options, as there is little information on the topic.
What is better in this situation?