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The previous aggressively unhelpful speaker deleted his answer, recommending that I, as a very smart person, answer for it:
VKontakte services are nothing but newfangled VK Apps .
BackEnd for them can be written in anything, even in python, even in PHP, even in node.js. BUT , are you more interested in how to make the same interesting single-page applications as in the examples on the first link? So, there are simply no alternatives to Javascript in FrontEnd.
Therefore, onlyyes, you can do something using Python and its frameworks, but you understand that in this way you will actually have no sane front-end, and such applications are primarily focused on user convenience, beauty and one-page - when moving through it is performed without reboot. Without the frontend, this will not work, and the frontend is javascript.
And what's the difference on what they write? Write in any language
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