Skeletal 2D animation in Unity3d: is it possible to change the animation of clothing polygon meshes when changing a character's clothing layer?

Question

Unity

If a character has a set of clothes, and each element of clothes behaves differently when running/hitting/jumping, that is, it has a different animation of polygon meshes, is it possible to implement a change of clothes along with a change of clothes animation? If you change only the clothes sprite, then the polygon meshes of the old clothes will remain.