replace doesn't work. I would be glad to help (without "learn python")?

Question

Python

I want to make a bot that encrypts a message, but replace() does not work

sh_txt = data['sh_txt']
  shifr = ''
  shifr += sh_txt
  
  shifr.replace('А', "Г")
  shifr.replace('а', 'г')
  shifr.replace('Б', "Д")
  shifr.replace("б", "д")
  shifr.replace("В", "Е")
  .............................
        #и так далее
  
  
  await msg.answer(f'{shifr}', reply_markup=gens)

Letter substitution does not work.
If I enter "A", the output is the same when it should be "G"

UPD:
I searched in Google. No need to say "google it" or "learn python"

Answer 1

shifr = 'АаБбВ'
mapping = {
    'А': 'Г',
    'а': 'г',
    'Б': 'Д',
    'б': 'д',
    'В': 'Е'
}
table = str.maketrans(mapping)
shifr = shifr.translate(table)

Answer 2

It is necessary not to search in Google, but to read the textbook.
PS We don't need to be told what to say.