Is it possible to run a Python script on an external device?

Question

Python

The essence of the problem: there is a Python script with external dependencies, in particular PyQT (as well as others).
Since PyQT is cross-platform, I'm going to run it on Windows, Linux, Mac (officially supported).
How to assemble a program from this with the elimination of all dependencies? So that you can store it on a portable device and run it from it? It also needs to be one file (see below).
Solutions:
For Windows, you can build an exe, for example, using PyInstaller (should work on all versions of Windows) - it suits.
With Unix, actually, and a hitch. There are a lot of options:
1) Wheels
2) Buildout
3) Virtualenv
And so on, I will immediately make a reservation that all dependencies must be removed without the Internet!
So far, the simplest, in my opinion, is to build Virtualenv and put it next to the script on a portable device. In the script, specify the path to the interpreter for the virtual environment (I did not check whether this would work).
Thus, we have 2 files program.exe and program.py. Windows user runs .exe, and Linux and Mac user .py
Tell me if my version will work or suggest your own.

Answer 1

docs.python-guide.org/en/latest/shipping/freezing