Is it possible to make printable poster layouts with html+css?

Question

css

There is a task - to create a lot of poster layouts in A2-A0 formats, mostly with text + icons.
The information for filling the posters is partly in the database and from there it could be pulled using php, and the same pieces of posters could be loaded with a template.
Polurkal, I saw that css supports CMYK, which means that something can already be done.
Is there any framework like bootstrap for this? And how can you save to ... pdf or tiff from the web with CMYK preservation and DPI selection?