How to use regular expressions to replace characters in the found substring?

Question

Regular Expressions

There is a text example

"dsdf"sdfsdf 
sdfsdfsd <script ssd="df">alert("1");</script>
sdfs " sdfsdf"a sdf"

You need to use a regular expression to find the text between <script и </script>and replace certain characters in it. Is it real?
The solution is needed in ColdFusion, but at least I understand whether it is possible to do this with regular expressions in general.
Thanks