How to set multiple options for escaping in Zend Framework?

Question

PHP

When I do this

$update->set([
            'content' => new Expression("REPLACE(content, '?', '?')", [$_query, $_replace]),
]);

error
SQLSTATE[HY093]: Invalid parameter number: number of bound variables does not match number of tokens

Tried instead of a question mark :query and :replace does not help. Can't find settings