How to protect yourself from imacros and other clickers?

Question

JavaScript

Users in one browser game use imacros and similar garbage.
What are efficient ways to define this plugin?
So far I'm only doing traffic analysis, but maybe there are more effective options.

Answer 1

Captcha, time between clicks. Heuristics are needed, it is necessary to identify a deviation from natural behavior. We need more information, where they click on what, how often, etc.