How to forward a port to another network in iptables?

Question

iptables

Hello !
Is it possible to make a port redirect to another network using iptables.
For example
Network interface
abcd/24
All that comes to port xxx is redirected to ip
wxyz
port yyy
As far as I understand iptables can only redirect within its own subnet.
-A PREROUTING -d 192.168.249.253 -p tcp -m tcp --dport 58641 -j DNAT --to-destination 192.168.254.150:58641
Or do I need to write some other rule besides DNAT ?