How to disable js library when an event occurs?

Question

JavaScript

Good afternoon!

Is it possible to disable a library if it has already been initialized without a visible page reload?

I have a task to enable and disable the library at different screen resolutions.
I tried to add a script connection to the markup and remove classes, I did all this, but now I understand that all this is useless. Because js has already added its classes and changed the html structure.

For me, this is not important, I just spent time solving all this, I don’t want everything to be empty ...

As I understand it, you need to at least disable initialization, disable styles and reload the page at the time the screen changes, at the backpoint .

Is it all useless work or is this how someone does it?