How in Django (MySQL) you can bulk update records in the database with different values?

Question

MySQL

There is a table

The table is planned to have about 100,000 records.
I need to select all the records, pass them through a number of methods (filter, calculate) and update the remaining ones (80,000 records may remain).
The trick is that when processing the table fields "left_points" and "right_points" - for each record there will be different ones.
Question. How to bulk update records with different values ​​as efficiently as possible?