How can I disable/toggle Selenium driver settings?

Question

Python

Before running the tests, there are preliminary driver settings, specifically the following:

capabilities = DesiredCapabilities.FIREFOX.copy()
capabilities["platform"] = "WINDOWS"
profile = FirefoxProfile()
profile.set_preference("intl.accept_languages", "ru")
driver = webdriver.Remote(desired_capabilities=capabilities, command_executor=selenium_grid_url, browser_profile=profile)

Is it possible, and if so how, to change the settings during the tests?
Specifically, you need to disable/change this parameter:
profile.set_preference("intl.accept_languages", "ru")