Flexbox, how to bind an element's position in a row?

Question

css

In short, even I’m a bit of a dinosaur and I’m late with practice on flex, I read it, played around and scored, and now I’m suffering ...
In general, I’m interested in such a moment, is it possible to stake an element at a certain position in a line (without using absolute positioning), for example, by center / right /left, regardless of the number of neighboring elements. Here's a little visualization of what I mean .
All that came to my mind was to make the elements columns and set their position through align-self, but the catch is that these are still columns and I can’t put them in a line.
Ps I know about hacks with margin left / right, but I need a single style, because suppose I don’t have information about which of the elements will disappear (right or left) in order to add margin.

Answer 1

You make all blocks order: 2, the first block that is needed on the left is order: 1 and the one at the end is order: 10