Different styles for two column list?

Question

css

There is a list like

<ul>
  <li>1</li>
  <li>2</li>
  <li>3</li>
  <li>4</li>
  <li>5</li>
  <li>6</li>
</ul>

The list is split into 2 columns using column-count.
How to set different styles for these columns?